Fixed a crash when computing alignments.Fixed a bug where “Find Protein Seuqence” was offered when pasting a sequence that contained non DNA characters into the Trace Viewer and Align dialog’s find controls.Right clicking on the reference sequence when aligning with a trace and invoking “Select Range…” had no effect.SnapGene now detects and refuses to open GIF, JPG, PNG and TIFF and SeqBuilder Project files.Fixed various glitches when closing open documents that have changes while they are shown with a manipulation or other dialog.Fixed a bug with decoding features and other data from Clone Manager files.Fixed a bug where after closing the Noncutters dialog, hiding and then restoring a document window would result in the Noncutters dialog reappearing.Fixed a bug that allowed multiples copies of SnapGene to be run simultaneously.Fixed a bug where attempting to add primers that hybridize around the numerical origin could cause the application to hang if features were visible just right of the origin.Fixed a bug where after aligning with a sequence trace, SnapGene did not default to that directory when aligning to additional sequences or opening new files.index extensions that are not SnapGene files. Fixed a bug where SnapGene would fail to properly open files with.Fixed a bug where when opening a GenBank file if the sequence length reported in the LOCUS field up top was incorrect due to a bug in Vector NTI, SnapGene might not import the entire sequence.Fixed a bug with decoding feature ranges from Vector NTI files.Added line breaks when exporting to FASTA.Various color, font, textual and alignment enhancements.Speed up fetching DNA for large sequences.Added a “Registration…” link to “Help” menu in the launch dialog.Added “ATG + GTG” and “ATG + GTG + TTG” to the list of start codon options in the “Translation Options” dialog.Added “AviTag™” to the list of “Epitope and Affinity Tags” in the Insertions tab of the Primer dialogs.Added “Plant Cells” and “Schizosaccharomyces pombe” to list of organisms in the description panel.Added “pUC19 – Sau3A I Digest” (General), “pHY Marker” (TaKaRa) and several Invitrogen MW Markers.Added “Thermo Scientific (Pierce)” to the list of predefined authors.Updated the Restriction Enzymes database including: -website links for Fermentas enzymes -updated buffer information for NEB enzymes -added PluTI -removed BfrBI and Bsp143II (both long discontinued) -removed NEB as a supplier for BstF5I (long discontinued).Changed the GenBank format names to “GenBank (standard)” and “GenBank (enhanced)”.Improved the default filename when exporting features or primers.Moved BLAST, alignment, gel simulation, and other commands to a new “Tools” menu and improved the organization of the File, Actions and Help menus.When adding a feature or primer or choosing enzymes, if the associate annotations are currently toggled off SnapGene will now offer to display them.While a list view has focus, Edit→Select All is now enabled and will select the entire contents.Improved auto scrolling the list features in the “Browse Common Features” dialog to first feature with typed letter.Improved the organization of feature types in the pull down menu found in the Add/Edit feature dialogs.Improved sorting of features/primers by name.If you select one or more codons and invoke “Make Feature”, the feature will now be translated by default.Enhanced the display of red boxes for discrepancies and yellow boxes for poor base calls when viewing alignments and aligned sequences.Substantially sped up scrolling while viewing alignments.Improved predicted sequence trace quality.Moved the “Add” button and added a “Remove” button to quickly adding/remove enzymes from Enzymes View.You can now view chromatogram data by clicking the associated button while viewing a sequence trace.Added a “Clear All” button to the “Edit References” dialog.Multiple sequence alignments with automatic trimming of aligned sequences.(better alignments, faster, supports sequences up to 1Mb)
Substantially improved alignment algorithm.
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